Depends on how much you hate your batteries. Or if your fingers can tolerate the cold.
Personally at that low temps... it's whoop season for a reason.
But if you really wanna fly outside make sure you keep those batteries warm, and understand their gonna get cold quick which degrades their performance. Maybe don't dip them below 3.8 average v/cell.
Also, keep in mind its gonna make your entire quad cold so it might be a bit more brittle (like the props).